The FilmArray is able to identify, in a closed system, dozens of the most lethal viruses and bacteria, including emerging infectious diseases. The easy-to-use, syringe-loaded system represents the next generation in automated detection systems.
The FilmArray uses a plastic pouch with automated capabilities, including sample preparation, reverse transcription for RNA viruses, and a two-stage nested multiplex PCR process. The results are a revolutionary detection system in a lightweight, small-footprint format.
Benefits from a Complete Product Solution
Multi-Use: Used for BioThreat Detection and Pandemic BioSurveillance.
Easy-to-Use: Automated protocol requires limited hands-on time and training.
Fully Automated: Sample prep, amplification, identification, and reporting.
Network: Interoperable with global information grid.
Single Instrument Integration: Reduce the amount of equipment and consumables.
Quick Test Times: Results in 1 hour.
Freeze-dried Reagents: Room temperature stable.
More BioThreat Targets: Test 16 pathogens in one run.
More Sample Types: Integrated sample prep removes PCR inhibitors and allows BioThreat detection in challenging environmental sample types such as soil and clay.
D.R. Seiner, H.A. Colburn, C. Baird, R.A. Bartholomew, T. Straub, K. Victry, J.R. Hutchison, N. Valentine, C.J. Bruckner‐Lea; Pacific Northwest National Laboratory, Chemical and Biological Signature Science Group, National Security Directorate, Richland, WA, USA; JournalofAppliedMicrobiology
To evaluate the sensitivity and specificity of the BioFire Diagnostics FilmArray system in combination with their Biothreat Panel for the detection of Bacillus anthracis (Ba), Francisella tularensis (Ft) and Yersinia pestis (Yp) DNA, and demonstrate the detection of Ba spores.
Elizabeth Wagar; University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Wagar E. 2016. Clin Microbiol Rev 29:175-189.
Regular review of the management of bioterrorism is essential for maintaining readiness for these sporadically occurring events. This review provides an overview of the history of biological disasters and bioterrorism. I also discuss the recent recategorization of tier 1 agents by the U.S. Department of Health and Human Services, the Laboratory Response Network (LRN), and specific training and readiness processes and programs, such as the College of American Pathologists (CAP) Laboratory Preparedness Exercise (LPX). LPX examined the management of cultivable bacterial vaccine and attenuated strains of tier 1 agents or close mimics. In the LPX program, participating laboratories showed improvement in the level of diagnosis required and referral of isolates to an appropriate reference laboratory. Agents which proved difficult to manage in sentinel laboratories included the more fastidious Gram-negative organisms, especially Francisella tularensis and Burkholderia spp. The recent Ebola hemorrhagic fever epidemic provided a check on LRN safety processes. Specific guidelines and recommendations for laboratory safety and risk assessment in the clinical microbiology are explored so that sentinel laboratories can better prepare for the next biological disaster.